Endocrine Abstracts

Muscle symptoms are the most common side effects of statin therapy and reasons for its discontinuation. Low serum vitamin D may contribute to statin-associated muscle symptoms (SAMS). The aim was to investigate the relationship between occurrence of SAMS and level of vitamin D (D), determine predictors of SAMS.Methods: 84 statin-treated patients were included in the study: 41 with SAMS (intolerant to ≥2 statins) and 43 patients without SAMS. We use...

Obesity is independently associated with poor control of blood pressure (BP) and weight reduction is generally recommended as the first line of treatment. However, the challenge remains to find the appropriate approach for weight reduction to influence BP status. The aim was to investigate the effect of non-pharmacologically and pharmacologically (metformin) induced weight loss on BP in obese hypertensive patients (HP). Methods: 100 HP (mean body mass in...